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COMMON MUTATIONS LINKED TO COMMON OBESITY IN EUROPEANS |
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Medicine
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Wednesday, 23 July 2008 19:49 |
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Scientists have discovered two common genetic mutations in people of European ancestry, which affect the production of several hormones controlling our appetite. The mutations have a significant effect on the risk of common obesity, according to research published in Nature Genetics. The PCSK1 gene codes for the proconvertase enzyme, which is responsible for producing fully functioning versions of hormones such as insulin, glugagon and melanocortin. These are all involved in controlling the rate of metabolism.
Changes in the PCSK1 gene cause relatively minor abnormalities in the proconvertase enzyme that it codes for. But the effect on the hormones is significant, as they all play a major role in regulating weight. Scientists from Imperial College London collaborated with teams from France, Denmark, Sweden and Germany to test the genomes of over 13,000 people. They discovered a significant association between the genetic mutations in PCSK1 and a tendency to develop obesity in both adults and children. |
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MIT REPORTS FINER LINES FOR MICROCHIPS |
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Nanotechnology
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Wednesday, 23 July 2008 19:46 |
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MIT researchers have achieved a significant advance in nanoscale lithographic technology, used in the manufacture of computer chips and other electronic devices, to make finer patterns of lines over larger areas than have been possible with other methods. Their new technique could pave the way for next-generation computer memory and integrated-circuit chips, as well as advanced solar cells and other devices.
The team has created lines about 25 nanometers (billionths of a meter) wide separated by 25 nm spaces. For comparison, the most advanced commercially available computer chips today have a minimum feature size of 65 nm. Intel recently announced that it will start manufacturing at the 32 nm minimum line-width scale in 2009, and the industry roadmap calls for 25 nm features in the 2013-2015 time frame. |
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PROCESS USED BY MICROBES TO MAKE GREENHOUSE GASES UNCOVERED |
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Biology
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Wednesday, 23 July 2008 19:34 |
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Researchers here now have a picture of a key molecule that lets microbes produce carbon dioxide and methane – the two greenhouse gases associated with global warming. The findings relate to organisms called methanogens and are explained in the latest issue of the journal Proceedings of the National Academy of Sciences.
The publication capped a 12-year effort and can offer some insights into how industrial processes might be improved, explained Michael Chan, professor of biochemistry, and Joseph Krzycki, professor of microbiology, both of Ohio State University. “This enzyme is the key to the whole process of methanogenesis from acetic acid,” Krzycki said. “Without it, this form of methanogenesis wouldn’t happen. Since it is so environmentally important worldwide, the impact of understanding this would be enormous.” |
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DESERT PLANT MAY HOLD KEY TO SURVIVING FOOD SHORTAGE |
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Biology
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Wednesday, 23 July 2008 19:24 |
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Scientists at the University of Liverpool are investigating how a Madagascan plant could be used to help produce crops in harsh environmental conditions.
The plant, Kalanchoe fedtschenkoi, is unique because, unlike normal plants, it captures most of its carbon dioxide at night when the air is cooler and more humid, making it 10 times more water-efficient than major crops such as wheat. Scientists will use the latest next-generation DNA sequencing to analyse the plant’s genetic code and understand how these plants function at night. |
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BIRDS MIGRATE TOGETHER AT NIGHT IN DISPERSED FLOCKS |
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Zoology
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Wednesday, 23 July 2008 19:40 |
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A new analysis indicates that birds don’t fly alone when migrating at night. Some birds, at least, keep together on their migratory journeys, flying in tandem even when they are 200 meters or more apart. The study, from researchers at the University of Illinois and the Illinois Natural History Survey, appears this month in Integrative and Comparative Biology. It is the first to confirm with statistical data what many ornithologists and observers had long suspected: Birds fly together in loose flocks during their nocturnal migration.
Researchers have spent decades trying to determine how birds migrate at night, when most bird migration occurs. But nighttime tracking of tiny flying objects a quarter mile to a half mile up is no easy task. They have used stationary light beams, radar-mounted tracking spot lamps and long-range radar to try to figure out what is going on in the night sky. Some have even watched birds cross the face of the moon. |
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PERCEPTION OF HOLE SIZE INFLUENCED BY PERFORMANCE |
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Medicine
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Wednesday, 23 July 2008 19:30 |
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Golfers who play well are more likely to see the hole as larger than their poor-playing counterparts, according to a Purdue University researcher. "Golfers have said that when they play well the hole looks as big as a bucket or basketball hoop, and when they do not play well they've been quoted as saying the hole looks like a dime or the inside of a donut," said Jessica K. Witt, an assistant professor of psychological sciences who studies perception in athletes. "What athletes say about how they see the hole and how well they play is true. We found golfers who play better judge the hole to be bigger than golfers who did not play as well.
"We know a relationship exists between performance and perception, but we are uncertain how they affect each other. For example, do golfers see the hole as bigger so they putt better? Or if they putt better, does that mean they see the hole as bigger? I believe it is a cyclical relationship, but more studies are needed to clarify if one affects the other." |
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CONTROLLING THE SIZE OF NANOCLUSTERS: FIRST STEP IN MAKING NEW CATALYSTS |
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Chemistry
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Tuesday, 22 July 2008 20:09 |
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Researchers from the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Stony Brook University have developed a new instrument that allows them to control the size of nanoclusters — groups of 10 to 100 atoms — with atomic precision. They created a model nanocatalyst of molybdenum sulfide, the first step in developing the next generation of materials to be used in hydrodesulfurization, a process that removes sulfur from natural gas and petroleum products to reduce pollution. As reported in the July 9, 2008 online edition of the Journal of Physical Chemistry C, the scientists made size-selected molybdenum sulfide nanoclusters as gaseous ions, and then gently deposited the clusters on a gold surface. The nanoclusters interact weakly with the gold support and therefore remain intact.
"With this new instrument, we can control how many and what type of atoms are in a nanocluster," said Brookhaven chemist Michael White, the principal author of the paper. "This knowledge enables us to make nanoclusters with predetermined size, structure and chemical composition, all which are important for the design of new catalysts." |
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